Slow Down Aging – This is the Best Way An impressive body of new research shows that this kind of exercise slows, and in some ways reverses, the body's internal clock.

In my gym, I overheard a conversation between a weightlifting trainer — who was in his mid-60s but looked about 50 — and an overweight client.

“I’m losing muscle mass because I’m getting older,” groused the client.

“No, you are getting older because you’re losing muscle mass,” responded his age-defying coach with a grin. “So let’s get to work!”

The trainer’s pep talk may sound like wishful thinking, but it’s got rock-solid science behind it.

An impressive body of new research shows that weight training — known to exercise researchers as resistance training — really does turn back the clock in important ways.

Even better, you needn’t put in Schwarzenegger-ish workouts to realize those benefits. Even modest resistance training yields huge age-reversing results.

That’s why I put weight training front and center among methods to keep my biological age a solid 25 years lower than my chronological age. 

So let’s do a few more reps on the issue…

“An impressive body of new research shows that this fix really does turn back the clock in important ways.”

Muscles Matter

In our appearance-besotted culture, building robust muscles can seem nothing more than a vanity project.

But muscles are vital metabolic organs — ones that, in our later years, are constantly under attack.

From roughly age 30 onward, muscle mass as a percentage of overall body weight starts to decline if no measures are taken to halt the process.

This shrinkage picks up truly terrifying speed at age 50.

Research shows that without intervention (in other words, exercise beyond a typical American’s daily activity), after age 50, we lose 1–2 percent of muscle mass and 1.5–5 percent of muscle strength each year.1

The results of unchecked muscle loss? A bigger risk of the familiar grab bag of maladies that make up what researchers call the “diseases of aging,” especially heart disease,2 Alzheimer’s disease3 and even cancer.4

There also appears to be a strong correlation between muscle mass and brain function — research says they shrink or grow more or less in tandem.5

All of which would be depressing if there was nothing we could do to reverse the effect of our muscles withering as we age.

But there is…

My favorite age-reversing gadget…

Just Lift It!

One of the best studies to summarize the health benefits of resistance training was published in Current Sports Medicine Reports.6 Dr. Wayne Westcott exhaustively compiled research on the health and healing effects of weight training and found that its benefits include:

“Improved physical performance, movement control, walking speed, functional independence, cognitive abilities and self-esteem.”

In other words, pretty much every attribute associated with a quality life.

And in terms of keeping disease at bay, he found resistance training can help to manage and/or prevent:

• Type 2 diabetes, by decreasing belly fat and improving insulin sensitivity

• Cardiovascular disease, by reducing resting blood pressure, decreasing low-density lipoprotein (LDL, or “bad”) cholesterol and triglycerides and increasing high-density lipoprotein (HDL, or “good”) cholesterol

• Osteoporosis, by promoting bone development, with studies showing a 1–3% increase in bone mineral density in response to weight training

• Low back pain and discomfort associated with arthritis and fibromyalgia

• “Aging factors” in skeletal muscle.

Wait a Sec. What Was That Last One?

Folks, weightlifting’s ability to reverse aging at the cellular level is where this gets reallyinteresting.

As you may recall from the October 2016 issue, mitochondria are the tiny “power plants” that feed energy to your body’s cells.

Chronic exposure to stressors that damage mitochondria — such as smoking, excessive drinking, chronically high blood sugar, pesticides or radiation — can raise your risk of cancer.

In fact, the Warburg hypothesis says that cancer is almost entirely due to mitochondrial dysfunction.

If that hypothesis is correct, and I believe it is, it means that anything you do to boost your mitochondrial health will also help prevent cancer.

With all this in mind, now read carefully Dr. Westcott’s conclusion about weight training:

There is evidence that circuit (short rest) resistance training can increase both the mitochondrial content and the oxidative capacity of muscle tissue. Another study, using standard resistance training, showed a reversal in mitochondrial deterioration that typically occurs with aging. After six months of resistance training, the older adult participants (mean age of 68 years) experienced gene expression reversal that resulted in mitochondrial characteristics similar to those in moderately active young adults (mean age of 24 years). The favorable changes observed in 179 genes associated with age and exercise led the researchers to conclude that resistance training can reverse aging factors in skeletal muscle…

Wow. Just wow.

“When it comes to exercise, frequency and intensity don’t matter nearly as much as regularity. So in the beginning, your goal should simply be to show up.”

What About Aerobics?

For roughly the last 50 years, the standard mainstream health advice has been to eat a high-carbohydrate, low-fat, semi-vegetarian diet and jog a few miles every day.

Long-suffering readers are, I hope, now aware that the first part of this advice is pure nonsense. High-carb, low-fat diets set the stage for a massive obesity and diabetes epidemic that began in the late 1970s and continues to this day.

As a guy who spent three decades — from age 20 to 50 — running pretty intensively and not having much except sore knees to show for it, it’s now clear to me that the second part of this advice was also less than stellar.

Because of the unique hazards associated with intense aerobic exercise, including a high risk of injury, it’s simply a questionable choice for a main exercise activity.

I am in favor of moving, whether in the form of long walks or pleasant bike rides, but particularly as we move into our 50s and beyond, a disciplined program of weight training offers more metabolic advantages and fewer risks.

Bottom Line

I understand this may not be what you want to hear. Perhaps you’ve never considered yourself a “gym person.”

But you don’t have to tackle this alone. To begin a weightlifting program, make an appointment with a trainer at a local gym. He or she will show you how to use the machines, teach you proper form and develop a program to help you reach your goals.

If you are over 50 and/or hampered by illness or injury, I would encourage you to not use that as an excuse to sit this out. Even modest resistance training programs have profound benefits. In fact, much of the research I’ve cited above is based on programs of no more than 90 total minutes per week, using modest weights.

I am a particular fan of Dumbbell Strength Training for Seniors. This eight-exercise program is within the capacity of virtually any ambulatory person, can be completed in a gym or at home in about 30 minutes and, when done twice a week, can yield dramatic improvements in physical and mental health.

When it comes to exercise, I always say frequency and intensity don’t matter nearly as much as regularity. So in the beginning, your goal should simply be to show up. Commit to a program of two or three times a week. And then, over time, you’ll be able to steadily increase the weight as you become stronger.

To Your Robust Health

Brad Lemley


  1. Keller K, Engelhardt M. Strength and muscle mass loss with aging process. Age and strength loss. Muscles Ligaments Tendons J. 2013
  2. Artero EG, Lee DC, Lavie CJ, et al. Effects of muscular strength on cardiovascular risk factors and prognosis. J Cardiopulm Rehabil Prev. 2012
  3. Boyle PA, Buchman AS, Wilson RS, Leurgans SE, Bennett DA. Association of muscle strength with the risk of Alzheimer disease and the rate of cognitive decline in community-dwelling older persons. Arch Neurol. 2009
  4. Ruiz JR, Sui X, Lobelo F, et al. Muscular strength and adiposity as predictors of adulthood cancer mortality in men. Cancer Epidemiol Biomarkers Prev. 2009
  5. Bolandzadeh N, Tam R, Handy TC, et al. Resistance Training and White Matter Lesion Progression in Older Women: Exploratory Analysis of a 12-Month Randomized Controlled Trial. J Am Geriatr Soc. 2015
  6. Westcott WL. Resistance training is medicine: effects of strength training on health. Curr Sports Med Rep. 2012

Brad Lemley

Brad Lemley

About Brad Lemley

I am a science journalist who has written for the Washington Post, Discover Magazine and dozens of other national publications. I've written or co-written 10 books, most on health and fitness. I am a passionate advocate for self-directed, nature-based health care, and believe strongly that robust health is within reach of anyone who possesses the right information.